Amino Acids, Peptides and Proteins in Organic Chemistry. Volume 3: Building Blocks, Catalysis and Coupling Chemistry

Amino Acids, Peptides and Proteins in Organic Chemistry. Volume 3: Building Blocks, Catalysis and Coupling Chemistry

2011-01-25 | ISBN: 3527321020 | PDF | 604 Pages | 5.87 MB

This is the third of five books in the Amino Acids, Peptidesand Proteins in Organic Synthesis series.
Closing a gap in the literature, this is the only series tocover this important topic in organic and biochemistry. Drawingupon the combined expertise of the international "who's who" inamino acid research, these volumes represent a real benchmark foramino acid chemistry, providing a comprehensive discussion of theoccurrence, uses and applications of amino acids and, by extension,their polymeric forms, peptides and proteins.
The practical value of each volume is heightened by theinclusion of experimental procedures.
The 5 volumes cover the following topics:
Volume 1: Origins and Synthesis of Amino Acids
Volume 2: Modified Amino Acids, Organocatalysis and Enzymes
Volume 3: Building Blocks, Catalysis and Coupling Chemistry
Volume 4: Protection Reactions, Medicinal Chemistry,Combinatorial Synthesis
Volume 5: Analysis and Function of Amino Acids and Peptides
This third volume in the series presents an in depth account ofrecent developments in the (bio-)synthesis of amino acids andpeptides. Divided into two parts, the first section deals withamino acids as building blocks, including the generation ofalpha-amino acids, beta-lactams, and heterocycles. The secondsection is devoted to the synthesis of peptides, with the focus onsolid phase synthesis. However, solution phase peptide synthesis iscovered as well, as are topics such as coupling reagents, chemicalligation, peptide purification and automation.
Originally planned as a six volume series, Amino Acids,Peptides and Proteins in Organic Chemistry now completes withfive volumes but remains comprehensive in both scope andcoverage.

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