Amyloid Proteins: Methods and Protocols

English | ISBN: 161779550X | 2012 | PDF | 563 pages | 9,4 mb

Amyloid diseases are characterized by the deposition of insoluble fibrous amyloid proteins. The word ˇ°amyloidˇ± indicates a starch-like compound, and though a misnomer, continues to be the accepted term for this group of protein conformational disorders. The second edition of Amyloid Proteins expands upon the previous edition with current, detailed protocols for the preparation of amyloid and its precursors, specific analytical methods for studying these proteins, cell culture models and assays for production of amyloid proteins, and protocols for amyloid extraction from tissue, its detection in vitro and in vivo, as well as nontransgenic methods for developing amyloid mouse models.


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